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Robert Hendrickson, one of the authors of the case report. However, previous studies on people and animals have shown that Garcinia cambogia may, indeed, increase serotonin levels.
And taking the supplement in combination with antidepressants known as selective serotonin reuptake inhibitors SSRIs , which also cause serotonin levels to rise, could lead to serotonin toxicity, said Hendrickson, a toxicologist at the Department of Emergency Medicine of Oregon Health and Sciences University. Hendrickson added that, based on the animal and human data suggesting both SSRIs and Garcinia increase serotonin levels, he recommends that people who are taking an SSRI not use Garcinia , at least until further research is done.
Garcinia cambogia , also known as tamarind, is a small, pumpkin-shaped fruit, and diet supplements made from it are touted for helping people lose weight.
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However, researchers have so far found only mixed results when looking at whether the supplement really helps weight loss. And one study in rats suggested that extremely high doses of Garcinia may cause testicular atrophy, and toxicity. The woman in the case report had been previously diagnosed with serotonin toxicity while she was taking a different kind of antidepressant.
At that time, she had also been taking Garcinia for a month or two, but she didn't tell the doctor who prescribed her antidepressant that she had also been taking the weight-loss supplement , Hendrickson said. Therefore, her doctor attributed her first case of serotonin toxicity to her first antidepressant, and switched her to another one. The researchers said they cannot be absolutely sure that it was, indeed, the use of Garcinia that caused the patient to develop serotonin toxicity.
Another potential, but less likely, trigger of the reaction, could have been the SSRI that she had been taking. Moreover, it is also possible that although the supplement she was taking was labeled as Garcinia, it might not have contained the supplement, but rather some other substance, Hendrickson said. Medications are highly regulated. This chemical helps curb cravings and appetite.
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It also regulates bowel movements of the body. Improves mood. Serotonin affects our emotion. A higher serotonin level improves the mood of an individual.
Garcinia Cambogia: Weight-Loss Supplement May Be Toxic to Some | Live Science
In addition, there are studies suggesting that serotonin can help with depression. Blocks fat formation. The active ingredient HCA blocks the enzyme that the body uses to form fats. It also decreases the production of bad cholesterol. Reduces the risk of developing type 2 diabetes. The fruit can help decrease glucose or blood sugar levels of the body.
Garcinia Cambogia Extract – What You Need To Know
However, this is not recommended for people who are already diabetic. If you want to try this supplement but are currently in other forms of medication, ask your doctor first for approval. Common side effects include headache, dizziness, dry mouth, and nausea. When a person is on ketosis, the body uses fat as a fuel or energy source instead of carbohydrates. As a result, the individual is able to burn more fat and lose more weight in the process. Meanwhile, garcinia cambogia helps block fat formation in the body.
Garcinia Cambogia: Safe for Weight Loss?
Instead, the body now uses the fat as additional fuel. When you combine the ketogenic diet with the intake of this supplement, the weight-loss effect is assumed to be more effective.
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It can help lower blood sugar level in the body. It also suppresses appetite and improves body metabolism. Thus, apple cider vinegar is considered to be an effective tool for weight loss. Many believe that combining apple cider vinegar with this fruit will improve weight loss results.
Dosage considerations for Garcinia cambogia extract
However, this assumption has no clinical basis yet. Garcinia cambogia is a tropical fruit not common in New Zealand. To date, there are only a few clinical studies about its effectiveness in losing weight.