You should not use methotrexate if you are allergic to it. Methotrexate should not be used to treat psoriasis or rheumatoid arthritis if you have:. Methotrexate is sometimes used to treat cancer in people who have a condition listed above. Your doctor will decide if this treatment is right for you. However, methotrexate may cause injury or death to an unborn baby and should not be used during pregnancy to treat arthritis or psoriasis. Tell your doctor if you are pregnant.
Methotrexate can harm an unborn baby if the mother or the father is using this medicine. This medicine may affect fertility ability to have children in both men and women. However, it is important to use birth control to prevent pregnancy because methotrexate may harm the baby if a pregnancy does occur. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Methotrexate is usually given once per week. You must use the correct dose. Some people have died after incorrectly using methotrexate every day. Methotrexate is injected into a muscle, under the skin, or as an infusion into a vein. A healthcare provider will give you this injection and may teach you how to properly use the medication by yourself.
Methotrexate may also be injected by a healthcare provider directly into a joint, or into the space around your spinal cord. Read and carefully follow any Instructions for Use provided with your medicine. You may need to mix methotrexate with a liquid diluent before using it. Ask your doctor or pharmacist if you don't understand all instructions. Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine. Methotrexate can be toxic to your organs, and may lower your blood cell counts.
You will need frequent medical tests, and you may need an occasional liver biopsy or chest X-ray. Your cancer treatments may be delayed based on the results. If you need to be sedated for dental work, tell your dentist you currently use methotrexate.
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Store methotrexate in its original packaging at room temperature away from moisture, heat, and light. Do not freeze. A single-use vial bottle or auto-injector is for one use only. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Is methotrexate causing my weight loss and decreased appetite?
New discussion Reply. Yes this drug can cause both wieght gain and loss. But contact your doctor if you are conserned. They should help. I have been on this drug for over a year I would love to have a poor appitite as I have now reached kg. I understand my problem is to do with having both rhumatoid artheritis sorry if spelling is wrong and fybromialgia. And now needing a wheelchair to go any distance.
I only take folic acid once a week and I take 2 hydroxychloroquine mg each day. I have to say it could be different meds as I live in the north. Hi Mary i have been on a similar regime to you for the last 3 years and have found a very gradual increase in gastro discomfort and bloating particularly if I eat too much. Hi MAry. Everyone is so different with how they react to Methotrexate.
Its a very strong drug clearly. The risk that you will develop liver damage may also be higher if you are elderly, obese, or have diabetes. Tell your doctor if you are taking any of the following medications: acitretin Soriatane , azathioprine Imuran , isotretinoin Accutane , sulfasalazine Azulfidine , or tretinoin Vesanoid. Ask your doctor about the safe use of alcoholic beverages while you are taking methotrexate. Call your doctor immediately if you experience any of the following symptoms: nausea, extreme tiredness, lack of energy, loss of appetite, pain in the upper right part of the stomach, yellowing of the skin or eyes, or flu-like symptoms.
Your doctor may order liver biopsies removal of a small piece of liver tissue to be examined in a laboratory before and during your treatment with methotrexate. Methotrexate may cause lung damage.
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Tell your doctor if you have or have ever had lung disease. Call your doctor immediately if you experience any of the following symptoms: dry cough, fever, or shortness of breath. Methotrexate may cause damage to the lining of your mouth, stomach, or intestines. Tell your doctor if you have or have ever had stomach ulcers or ulcerative colitis a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum.
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If you experience any of the following symptoms, stop taking methotrexate and call your doctor right away: mouth sores, diarrhea, black, tarry, or bloody stools, or vomit that is bloody or looks like coffee grounds. Taking methotrexate may increase the risk that you will develop lymphoma cancer that begins in the cells of the immune system. If you do develop lymphoma, it might go away without treatment when you stop taking methotrexate, or it might need to be treated with chemotherapy.
If you are taking methotrexate to treat cancer, you may develop certain complications as methotrexate works to destroy the cancer cells. Your doctor will monitor you carefully and treat these complications if they occur. Methotrexate may cause serious or life-threatening skin reactions. If you experience any of the following symptoms, call your doctor immediately: fever, rash, blisters, or peeling skin.
Methotrexate may decrease the activity of your immune system, and you may develop serious infections.
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Tell your doctor if you have any type of infection and if you have or have ever had any condition that affects your immune system. Your doctor may tell you that you should not take methotrexate unless you have life-threatening cancer.
If you experience signs of infection such as a sore throat, cough, fever, or chills, call your doctor immediately. If you take methotrexate while you are being treated with radiation therapy for cancer, methotrexate may increase the risk that the radiation therapy will cause damage to your skin, bones, or other parts of your body.
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Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before, during, and after your treatment to check your body's response to methotrexate and to treat side effects before they become severe. Tell your doctor if you or your partner is pregnant or plan to become pregnant. If you are female, you will need to take a pregnancy test before you begin taking methotrexate. Use a reliable method of birth control so that you or your partner will not become pregnant during or shortly after your treatment.
If you are male, you and your female partner should continue to use birth control for 3 months after you stop taking methotrexate. If you are female, you should continue to use birth control until you have had one menstrual period that began after you stopped taking methotrexate. If you or your partner become pregnant, call your doctor immediately. Methotrexate may cause harm or death to the fetus.
Methotrexate is used to treat severe psoriasis a skin disease in which red, scaly patches form on some areas of the body that cannot be controlled by other treatments. Methotrexate is also used along with rest, physical therapy, and sometimes other medications to treat severe active rheumatoid arthritis RA; a condition in which the body attacks its own joints, causing pain, swelling, and loss of function that cannot be controlled by certain other medications. Methotrexate is also used to treat certain types of cancer including cancers that begin in the tissues that form around a fertilized egg in the uterus, breast cancer, lung cancer, certain cancers of the head and neck, certain types of lymphoma, and leukemia cancer that begins in the white blood cells.
Methotrexate is in a class of medications called antimetabolites. Methotrexate treats cancer by slowing the growth of cancer cells. Methotrexate treats psoriasis by slowing the growth of skin cells to stop scales from forming.