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Alexa Actionable Analytics for the Web. Sell on Amazon Start a Selling Account. AmazonGlobal Ship Orders Internationally. Amazon Rapids Fun stories for kids on the go. ComiXology Thousands of Digital Comics. DPReview Digital Photography. It is contraindicated in patients with personal or family history of medullary thyroid carcinoma. Obesity medications are intended for long-term use, as obesity is a chronic disease. They improve health, quality of life, and body weight in patients with overweight and obesity.

Top Weight Loss Medications - Obesity Medicine AssociationMain

Medications for weight loss are only one component of a comprehensive treatment plan that also includes nutritional, physical activity, and behavioral therapies. The medicines currently available are appetite suppressants in some form. They help control hunger and cravings, so you can stick to your nutrition and exercise plan.

The only FDA-approved over-the-counter medicine for weight loss is Alli orlistat. The remainder of over-the-counter products are considered supplements. They are not regulated by the FDA and do not have proper studies to confirm their safety and effectiveness. These are only available through a prescription from a healthcare provider. Each one has certain indications based on the medical evaluation.

Obesity is a chronic disease that caused by multiple factors and is the leading risk factor for numerous other medical conditions. Therefore, it is important that your healthcare provider works with you to ensure you are on the safest and most effective medication. See author's posts. Many antidepressants are weight-positive cause weight gain , some are weight-neutral, and at least one is weight-negative cause weight loss. When starting an antidepressant, it is a good idea to speak with a healthcare provider about the different options and find a medication that will not cause weight gain.

Antidepressants are broken down into categories: selective serotonin reuptake inhibitors SSRIs , serotonin and norepinephrine reuptake inhibitors SNRIs , tricyclic antidepressants, monoamine oxidase inhibitors MAO inhibitors , and others. Medications within each of these categories can cause weight gain. Weight-positive medications in the tricyclic antidepressant category include Amitriptyline, Doxepin, and Imipramine. Desipramine, Nortriptyline, and Protriptyline have variable effects on weight.

Bupropion Wellbutrin , an aminoketone, is considered weight-negative and is prescribed both to assist in weight loss and to treat depression.


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However, people respond to antidepressants differently. Each medicine impacts appetite differently. Liraglutide is an injectable medication that acts on hormones from the gut that send signals to the brain to make you feel full quicker and decrease hunger signals. Lorcaserin is an oral medication that makes you feel full sooner by acting on serotonin, a neurotransmitter, in a part of the brain that controls appetite.

Naltrexone-bupropion also works in the brain, but on the pleasure-reward areas, to decrease cravings and appetite.

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Phentermine-topiramate is a combination of two medications that work together to decrease appetite and cravings. Topiramate also alters taste sensation, making food less enjoyable for some.

The stimulants all work in the brain to decrease appetite.